Zoloft has a half-life of about one day. That means that for every day that passes without taking the medication the level in the blood falls by 50%. After one day the level is reduced to 50% of the original level, after two days to 25%, after three days to 12.5%, & so on.
When one stops Zoloft too rapidly a withdrawal syndrome may develop. Among the symptoms that may be experienced r nausea, tremors, lightheadedness, muscle pains, weakness, insomnia, & anxiety. The withdrawal symptoms usually last 1-2 weeks but in some instances they may gradually decrease over a period as long as a month. It is generally recommended that one taper off this medication gradually under a doctor is supervision. Check with ur own personal physician for specific instructions.